Author

A. Piergentili

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Physiology· 1

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Assay:electrophysiology· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Lampert· 1 shared G. Rossetti· 1 shared P. C. T. d. Souza· 1 shared S. Albani· 1 shared V. S. B. Eswaran· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperPhysiology

A. Lampert

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1 paper

Recent·Most cited

Depletion of membrane cholesterol modifies structure, dynamic and activation of Nav1.7

S. Albani, V. S. B. Eswaran, A. Piergentili, P. C. T. d. Souza, A. Lampert, G. Rossetti

This study shows that cholesterol depletion alters Nav1.7 structure and function, affecting its gating and drug response, with implications for pain management.

bioRxiv · Feb 21, 2024Physiology