Depletion of membrane cholesterol modifies structure, dynamic and activation of Nav1.7
S. Albani, V. S. B. Eswaran, A. Piergentili, P. C. T. d. Souza, A. Lampert, G. Rossetti
This study shows that cholesterol depletion alters Nav1.7 structure and function, affecting its gating and drug response, with implications for pain management.
International Journal of Biological Macromolecules · Oct 1, 2024Peer-reviewedPhysiology