Fascin1 empowers YAP mechanotransduction and promotes cholangiocarcinoma development
A. Pocaterra, C. Ament, S. Ribbak, M. Evert, X. Chen, D. Calvisi, S. Dupont
This study identifies Fascin1 as a regulator of YAP mechanotransduction that promotes cholangiocarcinoma development by sustaining YAP activation in response to ECM cues.
bioRxiv · Nov 18, 2020Cancer Biology