Rapid GMP-compliant expansion of SARS-CoV-2-specific T cells from convalescent donors for use as an allogeneic cell therapy for COVID-19
R. S. Cooper, A. R. Fraser, L. Smith, P. Burgoyne, S. N. Imlach, L. M. Jarvis, S. Zahara, M. L. Turner, J. D. Campbell
The paper isolates and rapidly expands SARS-CoV-2-specific CD4+ and CD8+ T cells from convalescent donors under GMP standards, maintaining a central memory phenotype for therapeutic use in COVID-19.
bioRxiv · Aug 5, 2020Immunology