SCFFBXW11 complex targets interleukin-17 receptor A for ubiquitin-proteasome-mediated degradation.
B. Jin, S. A. Moududee, D. Ge, Y. Liu, A. R. Wang, P. Zhou, Z. You
The paper identifies FBXW11 as a ubiquitin ligase that targets IL-17RA for proteasomal degradation through lysine 27-linked polyubiquitin chains.
bioRxiv · Jun 21, 2023 · PreprintBiochemistry