A. Ramer-Tait

Alterations in the gut microbiome by HIV-1 infection or a high-fat diet associates with systemic immune activation and inflammation in double humanized-BLT mice

This study uses double humanized mice to show that HIV-1 infection and high-fat diet alter the gut microbiome, leading to immune activation and inflammation.

Stable Engraftment of a Human Gut Bacterial Microbiome in Double Humanized BLT-mice

This paper describes the successful engraftment of a stable human gut microbiome in double humanized BLT-mice to improve preclinical models for studying human disease.