Author

A. Schmoker

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

B.-W. Kim· 1 shared E. Park· 1 shared H. Jeon· 1 shared K. Song· 1 shared M. J. Eck· 1 shared S. Oh· 1 shared S. Rawson· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

B.-W. Kim

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1 paper

Recent·Most cited

Cryo-EM structure of a RAS/RAF recruitment complex

M. J. Eck, H. Jeon, E. Park, S. Rawson, A. Schmoker, B.-W. Kim, S. Oh, K. Song

The paper presents cryo-EM structures of a KRAS/BRAF/MEK1/14-3-3 complex, showing KRAS binding to BRAF's Ras-binding domain without activating it, suggesting stabilization of a pre-activation intermediate as a therapeutic target.

bioRxiv · Jul 14, 2022Biochemistry