Author

A. Semmelman

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Biochemistry· 1

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Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

A. E. van Vlimmeren· 1 shared D. Karandur· 1 shared N. H. Shah· 1 shared Z. Jiang· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperBiochemistry

A. E. van Vlimmeren

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1 paper

Recent·Most cited

Deep mutational scanning of a multi-domain signaling protein reveals mechanisms of regulation and pathogenicity

Z. Jiang, A. E. van Vlimmeren, D. Karandur, A. Semmelman, N. H. Shah

The paper uses deep mutational scanning to analyze SHP2 mutations, revealing diverse regulatory mechanisms and potential pathogenicity of uncharacterized variants.

bioRxiv · May 13, 2024 · PreprintBiochemistry