Author

A. Sepehri

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

B. Nepal· 3 shared T. Lazaridis· 3 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

2 top collaborators · 1 mutual co-author link

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3 shared papersBiophysics

B. Nepal

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3 papers

Recent·Most cited

Distinct modes of action of IAPP oligomers on membranes

A. Sepehri, B. Nepal, T. Lazaridis

The paper models and simulates pore formation by IAPP oligomers in membranes, finding distinct structural behaviors between helical and β-structured peptides.

bioRxiv · Jun 24, 2021Biophysics

Lipid interactions of an actinoporin pore-forming oligomer

A. Sepehri, B. Nepal, T. Lazaridis

This study uses molecular dynamics simulations to investigate how actinoporin oligomers interact with lipid membranes, finding that phase coexistence, not specific sphingomyelin recognition, drives membrane targeting.

bioRxiv · Oct 2, 2020Biophysics

Mechanism of negative membrane curvature generationby I-BAR domains

B. Nepal, A. Sepehri, T. Lazaridis

This study shows that I-BAR domains generate negative membrane curvature through their higher oligomeric structure, not their intrinsic dimer curvature.

bioRxiv · Aug 19, 2020Biophysics