Release of insulin granules by simultaneous, high-speed correlative SICM-FCM
J. Bednarska, P. Novak, Y. Korchev, P. Rorsman, A. Tarasov, A. Shevchuk
This study uses SICM-FCM to directly observe insulin granule exocytosis in pancreatic β-cells, revealing the kinetics of vesicle fusion and insulin crystal solubilization.
bioRxiv · Sep 17, 2020Cell Biology