Author
P. Novak
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2018-2026 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 21 mutual co-author links8 papers
Recent·Most cited
Development of a PNGase Rc column for online deglycosylation of complex glycoproteins during HDX-MS
T. O. T. Lambert, M. Gramlich, L. S. Stutzke, L. Smith, D. Deng, P. D. Kaiser, U. Rothbauer, J. L. Benesch, C. Wagner, M. Koenig, P. Pompach, P. Novak, A. Zeck, K. D. Rand
The paper develops a PNGase Rc column for online deglycosylation during HDX-MS, enabling efficient analysis of glycoproteins and mapping of mAb binding epitopes.
bioRxiv · Jul 28, 2023Biochemistry
The giant diploid faba genome unlocks variation in a global protein crop
M. Jayakodi, A. A. Golicz, J. Kreplak, L. I. Fechete, D. Angra, P. Bednar, E. Bornhofen, H. Zhang, R. Boussageon, S. Kaur, K. Cheung, J. Cizkova, H. Gundlach, A. Hallab, B. Imbert, , Mascher
The paper presents a high-quality chromosome-scale genome assembly of faba bean and uses it to develop a genotyping assay and dissect hilum color genetics, providing a genomics-based breeding platform for sustainable protein production.
bioRxiv · Sep 23, 2022Plant Biology
The Ecology of Palm Genomes: Repeat-associated genome size expansion is constrained by aridity
R. J. Schley, J. Pellicer, X.-J. Ge, C. F. Barrett, S. Bellot, M. Guignard, P. Novak, J. Suda, D. Fraser, W. J. Baker, S. Dodsworth, J. J. Macas, A. Leitch, I. J. Leitch
This study shows that aridity influences repeat community composition in palm genomes, with wetter environments associated with larger genomes and specific repeat expansions.
bioRxiv · Nov 4, 2021Evolutionary Biology
Hydroxyl radical footprinting analysis of a human haptoglobin-hemoglobin complex
D. S. Loginov, J. Fiala, P. Brechlin, G. Kruppa, P. Novak
The paper uses FPOP and mass spectrometry to identify oxidative modifications in the Hb-Hp complex, revealing residues involved in interactions and those affected by complex formation.
bioRxiv · Sep 20, 2021Biochemistry
In vitro evolution reveals primordial RNA-protein interaction mediated by metal cations
V. G. Giacobelli, K. Fujishima, M. Lepsik, V. Tretyachenko, T. Kadava, L. Bednarova, P. Novak, K. Hlouchova
This study uses in vitro evolution to show that RNA-protein interactions in early life could be mediated by metal cations and acidic residues instead of aromatic/basic amino acids.
bioRxiv · Aug 1, 2021 · PreprintBiochemistry
Release of insulin granules by simultaneous, high-speed correlative SICM-FCM
J. Bednarska, P. Novak, Y. Korchev, P. Rorsman, A. Tarasov, A. Shevchuk
This study uses SICM-FCM to directly observe insulin granule exocytosis in pancreatic β-cells, revealing the kinetics of vesicle fusion and insulin crystal solubilization.
bioRxiv · Sep 17, 2020Cell Biology
Cross-linking/Mass Spectrometry: A Community-Wide, Comparative Study Towards Establishing Best Practice Guidelines
C. Iacobucci, C. Piotrowski, R. Aebersold, B. C. Amaral, P. Andrews, C. Borchers, N. I. Brodie, J. E. Bruce, S. Chaignepain, J. D. Chavez, S. Claverol, J. Cox, G. Degliesposti, M. Q. Dong, N. Edinger, , Rand
This paper summarizes current XL-MS practices, compares strategies, and proposes common protocols to establish best practice guidelines for accurate and reproducible results.
bioRxiv · Sep 26, 2018 · PreprintBiochemistry