Author

A. Siemer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

A. Applebaum· 1 shared A. K. Okada· 1 shared F. Meier· 1 shared J. M. Isas· 1 shared K. Teranishi· 1 shared N. K. Pandey· 1 shared R. Langen· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

A. Applebaum

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1 paper

Recent·Most cited

Huntingtin fibrils with different toxicity, structure, and seeding potential can be reversibly interconverted

J. M. Isas, N. K. Pandey, K. Teranishi, A. K. Okada, A. Applebaum, F. Meier, R. Langen, A. Siemer

This study shows that HTTex1 fibrils with different toxicity and structure can be reversibly interconverted through changes in C-terminal domain dynamics.

bioRxiv · Jul 16, 2019 · PreprintBiophysics