Defining a Nonribosomal Specificity Code for Design
A. Stanisic, C.-M. Svensson, U. Ettelt, H. Kries
This study identifies a specificity code for nonribosomal peptide synthetases (NRPSs) by analyzing mutations in the adenylation domain, revealing how changes in specific residues affect substrate selectivity and enabling NRPS engineering.
bioRxiv · Aug 30, 2022 · PreprintBioengineering