Multi-omics approach reveals dysregulated genes during hESCs neuronal differentiation exposure to paracetamol
M. Spildrejorde, A. Samara, A. Sharma, M. Leithaug, M. Falck, S. Modafferi, A. Sundaram, G. Acharya, H. Nordeng, R. Eskeland, K. Gervin, R. Lyle
This study uses a multi-omics approach to investigate how paracetamol exposure affects neuronal differentiation of human embryonic stem cells, identifying dysregulated genes and chromatin changes linked to neurodevelopmental outcomes.
bioRxiv · Dec 8, 2022Cell Biology