Author

R. Eskeland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Research Focus:cell type annotation· 4 Approach:experimental assay· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:deep learning· 2 Assay:DNA methylation· 2

Frequent Co-Authors

A. Samara· 3 shared G. Acharya· 3 shared M. Falck· 3 shared M. Leithaug· 3 shared M. Spildrejorde· 3 shared R. Lyle· 3 shared A. Sharma· 2 shared K. Gervin· 2 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersCell Biology

A. Samara

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Author profile →

5 papers

Recent·Most cited

ANDA: An open-source tool for automated image analysis of neuronal differentiation

H. A. Waehler, N. A. Labba, R. E. Paulsen, G. K. Sandve, R. Eskeland

ANDA automates the analysis of neuronal morphology from live-cell imaging data, demonstrating accuracy and efficiency across rat, chicken, and human models.

bioRxiv · Apr 27, 2023 · PreprintCell Biology

Multi-omics approach reveals dysregulated genes during hESCs neuronal differentiation exposure to paracetamol

M. Spildrejorde, A. Samara, A. Sharma, M. Leithaug, M. Falck, S. Modafferi, A. Sundaram, G. Acharya, H. Nordeng, R. Eskeland, K. Gervin, R. Lyle

This study uses a multi-omics approach to investigate how paracetamol exposure affects neuronal differentiation of human embryonic stem cells, identifying dysregulated genes and chromatin changes linked to neurodevelopmental outcomes.

bioRxiv · Dec 8, 2022Cell Biology

A multi-omics approach to visualize early neuronal differentiation in 4D

A. Samara, M. Spildrejorde, A. Sharma, M. Falck, M. Leithaug, S. Modafferi, P. M. Bjornstad, G. Acharya, K. Gervin, R. Lyle, R. Eskeland

This paper develops a multi-omics protocol to study early human neuronal differentiation, identifying transcriptional waves and providing tools for data exploration.

bioRxiv · Feb 1, 2022 · PreprintCell Biology

Robust and reproducible neuronal differentiation of human embryonic stem cells for neurotoxicology

A. Samara, M. Falck, M. Spildrejorde, M. Leithaug, G. Acharya, R. Lyle, R. Eskeland

This paper describes a robust neuronal differentiation protocol from human embryonic stem cells for neurotoxicology, including optimized culture conditions and validation methods.

bioRxiv · Jan 26, 2022 · PreprintCell Biology

Pioneer transcription factors are associated with the modulation of DNA methylation patterns across cancers

R. Berhanu Lemma, T. Fleischer, E. Martinsen, M. Ledsaak, V. N. Kristensen, R. Eskeland, O. S. Gabrielsen, A. Mathelier

The paper identifies 13 transcription factors associated with DNA methylation modulation in cancer, showing their role in chromatin structure and transcription through emQTL analysis and experimental validation.

bioRxiv · May 10, 2021Cancer Biology