Author

A. T. Ho

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1

Frequent Co-Authors

L. D. Hurst· 2 shared A. Castillo Morales· 1 shared A. M. Rice· 1 shared B. Kinzel· 1 shared B. Young· 1 shared C. Mordstein· 1 shared C. Schmedt· 1 shared G. Kudla· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersEvolutionary Biology

L. D. Hurst

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Author profile →

3 papers

Recent·Most cited

Sequence conservation need not imply purifying selection: evidence from mammalian stop codon usage

A. T. Ho, L. D. Hurst

The paper shows that sequence conservation in mammalian stop codons can result from GC-biased gene conversion rather than purifying selection.

bioRxiv · Mar 2, 2022 · PreprintEvolutionary Biology

Evidence for strong mutation bias towards, and selection against, T/U content in SARS-CoV2: implications for attenuated vaccine design.

A. M. Rice, A. Castillo Morales, A. T. Ho, C. Mordstein, S. Mühlhausen, S. Watson, L. Cano, B. Young, G. Kudla, L. D. Hurst

The paper analyzes SARS-CoV-2 mutation patterns to show strong T/U mutation bias and selection against T, suggesting a strategy for vaccine attenuation by increasing usage of common synonymous codons.

bioRxiv · May 11, 2020 · PreprintEvolutionary Biology

Induction of muscle stem cell quiescence by the secreted niche factor Oncostatin M

S. C. Sampath, S. C. Sampath, A. T. Ho, S. Y. Corbel, J. D. Millstone, J. Lamb, J. Walker, B. Kinzel, C. Schmedt, H. M. Blau

This study identifies Oncostatin M as a secreted niche factor that induces muscle stem cell quiescence and maintains their regenerative capacity.

bioRxiv · Apr 18, 2018Cell Biology