Author

A. T. Londregan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

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Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Chaikuad· 1 shared D. R. Owen· 1 shared S. Knapp· 1 shared X. Ni· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBiochemistry

A. Chaikuad

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1 paper

Recent·Most cited

Structure and inhibitor binding characterization of oncogenic MLLT1 mutants

X. Ni, A. T. Londregan, D. R. Owen, S. Knapp, A. Chaikuad

The paper reports crystal structures of oncogenic MLLT1 mutants, showing conformational changes and altered histone binding, but demonstrates that these mutants can still be targeted by acetyllysine mimetic inhibitors.

bioRxiv · Feb 8, 2021Biochemistry