Virus-Like Particle Based-Vaccines Elicit Neutralizing Antibodies against the HIV-1 Fusion Peptide
A. T. Mogus, L. Liu, M. Jia, D. T. Ajayi, K. Xu, R. Kong, J. Huang, J. Yu, P. D. Kwong, J. R. Mascola, D. D. Ho, M. Tsuji, B. Chackerian
This study develops VLP-based vaccines targeting the HIV-1 FP8 epitope, showing they induce high-titer FP8-specific antibodies and effective neutralizing responses in mice.
bioRxiv · Sep 25, 2020Immunology