Predicting transdermal fentanyl delivery using mechanistic simulations for tailored therapy
T. Defraeye, F. Bahrami, L. Ding, R. I. Malini, A. Terrier, R. M. Rossi
This study uses mechanistic simulations to predict transdermal fentanyl delivery, showing significant variability in uptake by age and anatomical location, and demonstrating the potential of micron-sized reservoirs to enhance drug flux.
bioRxiv · Jun 16, 2020Bioengineering