Maturing neutrophils of lower density associate with thrombocytopenia in Puumala orthohantavirus-caused hemorrhagic fever with renal syndrome
L. E. Cabrera, J. Tietavainen, S. T. Jokiranta, S. M. Makela, A. Vaheri, J. Mustonen, O. Vapalahti, M. Kanerva, T. Strandin
The paper identifies and characterizes neutrophil subsets in PUUV-HFRS patients, finding that low-density granulocytes (LDGs) correlate with thrombocytopenia and may reflect increased bone marrow production.
bioRxiv · Feb 19, 2024Immunology