Comparative analysis of genome-wide protein-DNA interactions across domains of life reveals unique binding patterns for hypersaline archaeal histones
S. Sakrikar, R. K. Hackley, M. Martinez-Pastor, C. L. Darnell, A. Vreugdenhil, A. K. Schmid
This paper compares DNA binding patterns of halophilic histones to bacterial, archaeal, and eukaryotic DNA-binding proteins, revealing unique features in halophilic histones that suggest a role in transcriptional regulation rather than chromatin formation.
bioRxiv · Mar 22, 2022 · PreprintMicrobiology