Author

C. L. Darnell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Schmid· 2 shared R. K. Hackley· 2 shared A. K. Schmid· 1 shared A. Vreudenhil· 1 shared A. Vreugdenhil· 1 shared A. W. Bisson-Filho· 1 shared E. C. Garner· 1 shared J. Zheng· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersMicrobiology

A. Schmid

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3 papers

Recent·Most cited

A conserved transcription factor controls gluconeogenesis via distinct targets in hypersaline-adapted archaea with diverse metabolic capabilities

R. K. Hackley, A. Vreudenhil, C. L. Darnell, A. Schmid

The paper investigates the role of TrmB in regulating gluconeogenesis in two Haloarchaea with different metabolic capabilities, finding divergent regulatory mechanisms.

bioRxiv · Aug 19, 2023Microbiology

Comparative analysis of genome-wide protein-DNA interactions across domains of life reveals unique binding patterns for hypersaline archaeal histones

S. Sakrikar, R. K. Hackley, M. Martinez-Pastor, C. L. Darnell, A. Vreugdenhil, A. K. Schmid

This paper compares DNA binding patterns of halophilic histones to bacterial, archaeal, and eukaryotic DNA-binding proteins, revealing unique features in halophilic histones that suggest a role in transcriptional regulation rather than chromatin formation.

bioRxiv · Mar 22, 2022 · PreprintMicrobiology

The ribbon-helix-helix domain proteins CdrS and CdrL regulate cell division in archaea

C. L. Darnell, J. Zheng, S. Wilson, R. M. Bertoli, A. W. Bisson-Filho, E. C. Garner, A. Schmid

This study identifies and characterizes the CdrSL gene regulatory network in archaea, showing its role in regulating cell division through transcriptional control of FtsZ2.

bioRxiv · Jun 16, 2020 · PreprintMicrobiology