Author

A. W. Truman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:bacteria (other)· 4 Research Focus:cell type annotation· 4 Research Focus:gene regulatory network inference· 2 Assay:metabolomics· 2 Assay:metagenomics· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

N. M. Vior· 4 shared R. Lacret· 4 shared G. Chandra· 3 shared J. G. Malone· 2 shared J. Santos-Aberturas· 2 shared M. Trick· 2 shared T. H. Eyles· 2 shared A. D. Kingdon· 1 shared

Activity by Year

2017-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersMicrobiology

N. M. Vior

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Understanding the biosynthesis, metabolic regulation, and anti-phytopathogen activity of 3,7-dihydroxytropolone in Pseudomonas spp.

A. D. Moffat, L. Hoing, J. Santos-Aberturas, T. Markwalder, J. G. Malone, R. Teufel, A. W. Truman

This study identifies 3,7-dihydroxytropolone as a new antimicrobial compound produced by Pseudomonas, revealing its biosynthesis pathway and ecological relevance.

bioRxiv · Apr 3, 2024Microbiology

Pan-genome analysis identifies intersecting roles for Pseudomonas specialized metabolites in potato pathogen inhibition

A. Pacheco-Moreno, F. L. Stefanato, J. J. Ford, C. Trippel, S. Uszkoreit, L. Ferrafiat, L. Grenga, R. Dickens, N. Kelly, A. D. Kingdon, L. Ambrosetti, S. A. Nepogodiev, K. C. Findlay, J. Cheema, M. Trick, , A. W. Truman

The paper identifies specialized metabolites in Pseudomonas that inhibit potato pathogens in agricultural soil.

bioRxiv · Nov 10, 2021Microbiology

Vps501, a novel vacuolar SNX-BAR protein cooperates with the SEA complex to induce autophagy

S. Goyal, V. A. Segarra, A. M. Stecher, Nitika, A. W. Truman, A. M. Reitzel, R. J. Chi

This study identifies Vps501 as a novel SNX-BAR protein that cooperates with the SEA complex to regulate autophagy in yeast.

bioRxiv · May 6, 2021 · PreprintCell Biology

Discovery and characterisation of an amidine-containing ribosomally-synthesised peptide that is widely distributed in nature

A. H. Russell, N. M. Vior, E. S. Hems, R. Lacret, A. W. Truman

The paper identifies a novel amidine-containing RiPP family using genome mining and characterizes a representative member from Streptomyces albus.

Chemical Science · Jan 1, 2021Peer-reviewedMicrobiology

Understanding Thioamitide Biosynthesis Using Pathway Engineering and Untargeted Metabolomics

T. H. Eyles, N. M. Vior, R. Lacret, A. W. Truman

The paper uses pathway engineering and untargeted metabolomics to elucidate thioamitide biosynthesis and identify new RiPP gene clusters.

bioRxiv · Dec 17, 2020Microbiology

Tumor -Associated MUC1 Regulates TGF-β Signaling and Function in Pancreatic Ductal Adenocarcinoma

P. Grover, S. Nath, M. Bose, A. J. Sanders, C. Brouwer, N. Fnu, R. Zhou, M. Yazdanifar, M. Ahmed, S.-t. Wu, A. W. Truman, P. Mukherjee

This study shows that high tMUC1 expression in PDA correlates with altered TGF-β signaling, promoting tumor growth and resistance to TGF-β therapy.

bioRxiv · Apr 29, 2020 · PreprintCancer Biology

Uncovering the unexplored diversity of thioamidated ribosomal peptides in Actinobacteria using the RiPPER genome mining tool

J. Santos-Aberturas, G. Chandra, L. Frattaruolo, R. Lacret, T. H. Pham, N. M. Vior, T. H. Eyles, A. W. Truman

The paper introduces RiPPER, a tool for identifying RiPP precursor peptides, and uses it to discover new thioamidated RiPPs in Actinobacteria.

bioRxiv · Dec 13, 2018Microbiology

Discovery and biosynthesis of the antibiotic bicyclomycin in distant bacterial classes

N. M. Vior, R. Lacret, G. Chandra, S. Dorai-Raj, M. Trick, A. W. Truman

This paper identifies the biosynthetic gene cluster for bicyclomycin in Streptomyces cinnamoneus and discovers its presence in hundreds of Pseudomonas aeruginosa isolates across different bacterial classes.

bioRxiv · Dec 21, 2017Microbiology