A dual allosteric pathway drives human mitochondrial Lon
G. Valentin Gese, S. Shahzad, C. Pardo-Hernandez, A. Wramstedt, M. Falkenberg, B. M. Hällberg
This study reveals the dual allosteric mechanism of human mitochondrial Lon protease through cryo-EM and biochemistry, showing how coordinated ATP hydrolysis and substrate translocation occur.
bioRxiv · Jun 9, 2021 · PreprintBiochemistry