Author

G. Valentin Gese

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:cryo-EM· 3 Approach:experimental assay· 3 Research Focus:protein folding & dynamics· 3 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

A. Khawaja· 1 shared A. Wramstedt· 1 shared B. M. Hällberg· 1 shared C. Pardo-Hernandez· 1 shared E. Hurt· 1 shared I. Dr. Sinning· 1 shared J. Rorbach· 1 shared K. Lapouge· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperBiochemistry

A. Khawaja

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Author profile →

3 papers

Recent·Most cited

Structural inventory of cotranslational protein folding by the eukaryotic RAC complex

M. Kisonaite, K. Wild, K. Lapouge, G. Valentin Gese, N. Kellner, E. Hurt, I. Dr. Sinning

This study determines high-resolution cryo-EM structures of the RAC complex bound to the ribosome, revealing its conformational dynamics and interactions with Ssb during cotranslational protein folding.

bioRxiv · Jun 24, 2022 · PreprintBiochemistry

A dual allosteric pathway drives human mitochondrial Lon

G. Valentin Gese, S. Shahzad, C. Pardo-Hernandez, A. Wramstedt, M. Falkenberg, B. M. Hällberg

This study reveals the dual allosteric mechanism of human mitochondrial Lon protease through cryo-EM and biochemistry, showing how coordinated ATP hydrolysis and substrate translocation occur.

bioRxiv · Jun 9, 2021 · PreprintBiochemistry

Structural basis for late maturation steps of the human mitoribosomal large subunit

M. Cipullo, G. Valentin Gese, A. Khawaja, M. Hallberg, J. Rorbach

The paper determines cryo-EM structures of human mitoribosomes to elucidate late steps in large subunit biogenesis involving rRNA folding, methylation, and PTC formation.

bioRxiv · Mar 15, 2021Biochemistry