Practical guide to calculating impact of avidity in models of bispecific antibodies with two membrane-bound targets
I. Kareva, S. Kabilan, A. Zutshi, J. Rhoden
The paper explains how to calculate avidity's impact in a mathematical model of bispecific antibodies targeting two membrane-bound proteins, supporting model-informed drug discovery.
bioRxiv · Sep 12, 2022 · PreprintPharmacology & Toxicology