Structural basis of the allosteric regulation of cyanobacterial glucose-6-phosphate dehydrogenase by the redox sensor OpcA
Sofía Doello, Dmitry Shvarev, Marius L. Theune, Jakob Sauerwein, A.E. Klon, Erva Keskin, Marko Boehm, Kirstin Gutekunst, Karl Forchhammer
The paper investigates how OpcA regulates G6PDH in cyanobacteria through redox-dependent conformational changes, revealing a novel allosteric mechanism.
Proceedings of the National Academy of Sciences · Dec 6, 2024Peer-reviewedMolecular Biology