SCALLOPS: a scalable, integrated computational framework for Optical Pooled Screens
Joshua Gould, José Sergio Hleap, Ping Wu, Takamasa Kudo, Jane Guan, Anqi Zhu, Eric Lubeck, Xing-Yue M. Ge, Aaron Archer Waterman, Tommaso Biancalani, Orit Rozenblatt–Rosen, Ciara Metcalfe, Avtar Singh, David Richmond, Aviv Regev, Bo Li
SCALLOPS improves processing of optical pooled screens by enabling efficient alignment and analysis of large-scale image data, demonstrating superior performance over existing methods.
bioRxiv · Jun 16, 2026 · PreprintBioinformatics