Ping Wu

The paper introduces CellMAPP and CHART to analyze multiplexed antibody imaging data, revealing modular morphological programs in response to genetic perturbations.

SCALLOPS improves processing of optical pooled screens by enabling efficient alignment and analysis of large-scale image data, demonstrating superior performance over existing methods.

PerturbView enables highly multiplexed optical pooled screens in primary cells and tissues by improving barcode amplification, revealing regulators of NFκB signaling and enabling spatial transcriptomics integration.

The paper uses optogenetic control of Bicoid to study gap gene regulation dynamics in embryos, revealing both known and novel regulatory relationships.