Multi-omics analysis of AML cells treated with azacitidine reveals highly variable cell surface proteome remodeling
Kevin K Leung, Aaron Nguyen, Tao Shi, Lin Tang, Xiaochun Ni, Laure Escoubet, Kyle J MacBeth, Jorge DiMartino, James A Wells
This study examines how azacitidine affects the DNA methylome, transcriptome, and cell surface proteome of four AML cell lines, revealing pathway-level changes in metabolism and immune response.
bioRxiv · Jul 14, 2018 · PreprintCancer Biology