Author

Tao Shi

University of Pennsylvania

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Aaron Nguyen· 1 shared Alexa Betzig SchrockiD· 1 shared Anna Marie Pyle· 1 shared Arindam DattaiD· 1 shared Brennan James DeckeriD· 1 shared Chenming CuiiD· 1 shared Ethan S. SokoliD· 1 shared Fabio Guintini· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Aaron Nguyen

Author profile →

3 papers

Recent·Most cited

RNA-targeted aminopyridine compounds provide a new antifungal strategy

Jimin Hwang, Luke J Sisto, Tao Shi, Michael C Van Zandt, Anna Marie Pyle

The paper identifies aminopyridine compounds that target fungal group I introns, showing antifungal activity and synergy with amphotericin B.

bioRxiv · Nov 6, 2026 · PreprintBiochemistry

Landscape of reversion alterations in homologous recombination genes reveals evolutionary constraints

Brennan James Decker, Saumya Dushyant Sisoudiya, James Thornton, Chenming Cui, Taku Harada, Shahlo O. Solieva, Russell William Madison, Arindam Datta, Tao Shi, Fabio Guintini, Zoe Fleischmann, Mark Hartman, Shannon Terrell Bailey, Jeffrey A. Leibowitz, Ethan S. Sokol, , Katherine L. Nathanson

The paper identifies reversion mutations in homologous recombination genes across cancers, showing they restore DNA repair and confer PARP inhibitor resistance through specific structural alterations.

bioRxiv · May 27, 2026 · PreprintCancer Biology

Multi-omics analysis of AML cells treated with azacitidine reveals highly variable cell surface proteome remodeling

Kevin K Leung, Aaron Nguyen, Tao Shi, Lin Tang, Xiaochun Ni, Laure Escoubet, Kyle J MacBeth, Jorge DiMartino, James A Wells

This study examines how azacitidine affects the DNA methylome, transcriptome, and cell surface proteome of four AML cell lines, revealing pathway-level changes in metabolism and immune response.

bioRxiv · Jul 14, 2018 · PreprintCancer Biology