Author

Aaron P Ragsdale

National Laboratory of Genomics for Biodiversity

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:statistical model· 2 Organism:Drosophila· 1 Organism:human· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Alec J Coffman· 1 shared PingHsun Hsieh· 1 shared Ryan N Gutenkunst· 1 shared Travis J Struck· 1 shared

Activity by Year

2015-2021 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperEvolutionary Biology

Alec J Coffman

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2 papers

Recent·Most cited

Evolutionary BiologybioRxivMar 25, 2021

Local fitness and epistatic effects lead to distinct patterns of linkagedisequilibrium in protein-coding genes

Aaron P Ragsdale

The paper develops a numerical method to compute linkage disequilibrium patterns under selection and epistasis, showing that positive LD within conserved domains suggests compensatory mutations or antagonistic epistasis.

DOI 10.1093/genetics/iyac097

humanwhole-genome sequencing

𝕏 PostBluesky

Evolutionary BiologybioRxivOct 21, 2015

Inferring the correlated fitness effects of nonsynonymous mutations at the same site using triallelic population genomics

Aaron P Ragsdale, Alec J Coffman, PingHsun Hsieh…·Ryan N Gutenkunst

This study introduces a model to infer correlated fitness effects of nonsynonymous mutations at the same site using triallelic population genomics in D. melanogaster.

DOI 10.1534/genetics.115.184812

Drosophilastatistical model

𝕏 PostBluesky