The C. elegans ephrin EFN-4 functions non-cell autonomously with heparan sulfate proteoglycans to promote axon outgrowth and branching
Alicia A. Schwieterman, Alyse N. Steves, Vivian Yee, Cory J. Donelson, Aaron Pital, Taylor Voyles, Austin M. Howard, Danielle E. Ereddia, Kelsie S. Effrein, Jonathan L. McMurry, Brian D. Ackley, Andrew D. Chisholm, Martin L. Hudson
This study identifies EFN-4 as a non-cell autonomous ephrin in C. elegans that promotes axon outgrowth and branching through interactions with heparan sulfate proteoglycans.
bioRxiv · Jul 17, 2015 · PreprintDevelopmental Biology