In-silico and in-vitro morphometric analysis of intestinal organoids
Sandra Montes-Olivas, Danny Legge, Abbie Lund, Alexander George Fletcher, Ann Caroline Williams, Lucia Marucci, Martin Homer
This study develops an algorithm for counting crypt-like structures in intestinal organoids and modifies a 2D agent-based model to better simulate budding structures, showing improved agreement with experimental data.
bioRxiv · Dec 8, 2022 · PreprintSystems Biology