Danny Legge

This study shows PRMT5 inhibition targets MNA neuroblastoma by altering splicing of nutrient sensors and epitranscriptome regulators, leading to growth inhibition and apoptosis.

This study uses Mendelian randomization to assess the causal effect of obesity and related metabolic traits on oral and oropharyngeal cancer risk, finding limited evidence of a direct causal link.

This study develops an algorithm for counting crypt-like structures in intestinal organoids and modifies a 2D agent-based model to better simulate budding structures, showing improved agreement with experimental data.