BiochemistryProceedings of the National Academy of SciencesPeer-reviewed
Structure-guided aminoacylation and assembly of chimeric RNAs
Aleksandar Radakovic, Anna Lewicka, Marco Todisco…·Jack W. Szostak
The paper shows that specific RNA sequences can be nonenzymatically aminoacylated and ligated to form amino acid-bridged stem-loop RNAs, with structural and functional similarities to modern tRNA.
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