Author

Harry R. M. Aitken

Howard Hughes Medical InstituteORCID 0009-0006-4422-5959Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Jack W. SzostakiD· 2 shared Abdullah Bannan· 1 shared Aleksandar RadakoviciD· 1 shared Anna LewickaiD· 1 shared Ben W. F. ColvilleiD· 1 shared Christopher E. CarriD· 1 shared Daniel DuzdevichiD· 1 shared Joseph A. PiccirilliiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

Jack W. SzostakORCID

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2 papers

Recent·Most cited

Molecular BiologyNucleic Acids ResearchPeer-reviewedOct 14, 2024

Overcoming nucleotide bias in the nonenzymatic copying of RNA templates.

Daniel Duzdevich, Christopher E. Carr, Ben W. F. Colville…·Jack W. Szostak

This study demonstrates a method to overcome nucleotide bias in nonenzymatic RNA copying using a prebiotically plausible mixture of nucleotides and oligonucleotides.

10 citations

experimental assay

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BiochemistryProceedings of the National Academy of SciencesPeer-reviewedAug 23, 2024

Structure-guided aminoacylation and assembly of chimeric RNAs

Aleksandar Radakovic, Anna Lewicka, Marco Todisco…·Jack W. Szostak

The paper shows that specific RNA sequences can be nonenzymatically aminoacylated and ligated to form amino acid-bridged stem-loop RNAs, with structural and functional similarities to modern tRNA.

17 citations

proteomicsdeep learning

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