High-level ciprofloxacin resistance in Pseudomonas aeruginosa is associated with genomic adaptation, collateral antibiotic susceptibility, and physiological trade-offs
This study identifies genomic and physiological changes in Pseudomonas aeruginosa resistant to high-level ciprofloxacin, revealing mutations and trade-offs in antibiotic susceptibility.
bioRxiv · Jul 29, 2026 · PreprintMicrobiology