Interconnected axes of phenotypic plasticity drive coordinated cellular behaviour and worse clinical outcomes in breast cancer
Ritesh Kumar Meena, Yijia Fan, Soundharya Ramu, Anjaney J. Pandey, Abhinav Kannan, Yashvita Subramanian, Yukta Subramanian, Jason Thomas George, Mohit Kumar Jolly
The paper shows that interconnected axes of phenotypic plasticity in breast cancer drive coordinated cellular behavior and influence clinical outcomes through mutual inhibition between two teams of plasticity-related nodes.
bioRxiv · Nov 23, 2025 · PreprintSystems Biology