Author

Yijia Fan

Texas A&M Health Science Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Bioengineering· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 2 Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Jason Thomas GeorgeiD· 4 shared Mohit Kumar JollyiD· 2 shared Abhinav Kannan· 1 shared Anjaney J. Pandey· 1 shared Pujan ShresthaiD· 1 shared Ritesh Kumar Meena· 1 shared Sarthak SahooiD· 1 shared Soundharya RamuiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersBiophysics

Jason Thomas GeorgeORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Coupled SDE-ODE Modeling of Tumor-Immune Dynamics to Infer Biomarker Release

Pujan Shrestha, Yijia Fan, Jason Thomas George

This paper develops a coupled SDE-ODE model to infer tumor burden from biomarker signals by linking tumor-immune dynamics to ctDNA release.

Bulletin of Mathematical Biology · Jun 23, 2026Peer-reviewedBiophysics

Regulatory network and spatial modeling reveal cooperative mechanisms of resistance and immune escape in ER+ breast cancer

Yijia Fan, Sarthak Sahoo, Mohit Kumar Jolly, Jason Thomas George

This study models regulatory networks and spatial dynamics in ER+ breast cancer to show how resistance and immune escape co-occur and how combination therapies can counteract these mechanisms.

BMC Cancer · Feb 23, 2026Peer-reviewedBioengineering

Interconnected axes of phenotypic plasticity drive coordinated cellular behaviour and worse clinical outcomes in breast cancer

Ritesh Kumar Meena, Yijia Fan, Soundharya Ramu, Anjaney J. Pandey, Abhinav Kannan, Yashvita Subramanian, Yukta Subramanian, Jason Thomas George, Mohit Kumar Jolly

The paper shows that interconnected axes of phenotypic plasticity in breast cancer drive coordinated cellular behavior and influence clinical outcomes through mutual inhibition between two teams of plasticity-related nodes.

bioRxiv · Nov 23, 2025 · PreprintSystems Biology

Distinct evolutionary patterns of tumor immune escape and elimination determined by ECM architectures

Yijia Fan, Jason Thomas George

This study uses a computational model to show how tumor-associated collagen signatures influence immune escape and survival in breast cancer.

Journal of The Royal Society Interface · Jul 1, 2025Peer-reviewedBiophysics