Isolation of Chemically Cyclized Peptide Binders Using Yeast Surface Display
Kaitlyn B. Bacon, Abigail Blain, Matthew R. Burroughs, Nikki McArthur, Balaji M. Rao, Stefano Menegatti
This paper isolates and characterizes cyclic peptide binders using yeast surface display, showing they can bind targets like lysozyme and IL-17 with low micromolar to nanomolar affinities without chemical synthesis.
ACS Combinatorial Science · Aug 3, 2020Peer-reviewedSynthetic Biology