Structural modeling reveals the mechanism of motor ATPase coordination during type IV pilus retraction
Abigail E. Teipen, Jacob D. Holt, Diane L. Lynch, Yixuan Peng, Triana N. Dalia, James C. Gumbart, Carey D. Nadell, Ankur B. Dalia
The paper models and validates the coordination mechanism between PilT and PilU ATPases during type IV pilus retraction using AlphaFold 3 and molecular dynamics simulations.
Proceedings of the National Academy of Sciences · Jun 8, 2026Peer-reviewedMicrobiology