Grant J. Jensen

This study visualizes bacterial nanotube formation in Bacillus subtilis, revealing a novel membranous organelle called the tubeosome that facilitates intercellular communication.

This study uses cryo-ET to visualize NLRP3 inflammasome condensates at the MTOC during activation, revealing structural changes and pyroptosis in macrophages.

The paper uses electron cryo-tomography to determine the architecture of the Tad pilus in Caulobacter vibrioides and proposes an assembly model.

The paper presents a 3.3 Å cryo-EM map of Vibrio cholerae competence pilus and a full-length pseudoatomic model of the CPM, revealing unique structural features and mechanical properties.

The paper introduces MotorBench, a dataset of bacterial flagellar motors for testing automated detection algorithms in cryo-ET.

The paper demonstrates using optical interference in a cryogenic FIB-SEM-LM system to target lamella production beyond the diffraction limit for capturing virions in host cells.

The paper identifies Ribosome-Associated Vesicles (RAVs) as dynamic platforms that facilitate activity-dependent local translation in neurons by transporting ribosomes to distal processes.

This study uses cryo-electron tomography to reveal the structure of Anabaena flos-aquae gas vesicles, showing how GvpA subunits form the shell and how GvpC provides structural reinforcement.

This paper introduces a new cryogenic microscope that combines fluorescence, ion beam, and electron beam imaging to improve the targeting and fabrication of lamellae for high-resolution imaging.

This study shows that UVC irradiation at cryogenic temperatures can inactivate pathogens without damaging their structure, making them suitable for cryo-EM analysis.

The paper uses electron cryo-tomography to analyze membrane projections and associated protein complexes in bacterial species, identifying diverse structures and protein associations.

The paper introduces a computational method for designing rigid protein assemblies through three-body fusion and validates it experimentally with mass spectrometry and cryo-EM.

The paper introduces RegArch, a language for describing syntactic patterns in protein architectures, and provides a reference implementation to parse and match annotated proteins.

The paper observes stable sub-complexes in bacterial flagellar motors using cryo-tomography, suggesting a modular assembly pathway involving independent outer- and inner-membrane sub-complexes.

The paper uses cryo-electron tomography to analyze flagellar motor structures in three Gammaproteobacteria species, finding a correlation between stator type and structural complexity.

This study identifies DotU and IcmF as proteins mediating polar targeting and assembly of the Legionella Dot/Icm T4BSS, revealing an 'outside-inside' biogenesis mechanism.

The paper describes the molecular architecture of the Legionella Dot/Icm T4BSS using cryo-electron tomography, revealing a central channel and secretion chamber with 13-fold symmetry.