Indirect and Direct Cannabinoid Agonists Differentially Affect Mesolimbic Dopamine Release and Related Behaviors
Kevin M. Honeywell, Timothy G. Freels, Megan A. McWain, Abigail S. Chaffin, Hunter G. Nolen, Helen J.K. Sable, Deranda B. Lester
This study compares the effects of indirect and direct cannabinoid agonists on mesolimbic dopamine release and behaviors in mice, finding no abuse-related behaviors but suggesting direct CB1R agonism affects dopamine function more.
Behavioral Neuroscience · Apr 1, 2024Peer-reviewedNeuroscience