Author

Timothy G. Freels

University of MemphisORCID 0000-0002-8212-0844Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:rat· 3 Research Focus:cell type annotation· 1 Assay:electronic health records· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Deranda B. LesteriD· 2 shared Hayden R. WrightiD· 2 shared Janelle M. Lugo· 2 shared Ryan J. McLaughliniD· 2 shared Abigail S. Chaffin· 1 shared Amanda M BrowniD· 1 shared Brian H. ClowersiD· 1 shared Carrie CuttleriD· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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2 shared papersNeuroscience

Deranda B. LesterORCID

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Author profile →

4 papers

Recent·Most cited

Indirect and Direct Cannabinoid Agonists Differentially Affect Mesolimbic Dopamine Release and Related Behaviors

Kevin M. Honeywell, Timothy G. Freels, Megan A. McWain, Abigail S. Chaffin, Hunter G. Nolen, Helen J.K. Sable, Deranda B. Lester

This study compares the effects of indirect and direct cannabinoid agonists on mesolimbic dopamine release and behaviors in mice, finding no abuse-related behaviors but suggesting direct CB1R agonism affects dopamine function more.

Behavioral Neuroscience · Apr 1, 2024Peer-reviewedNeuroscience

Maternal cannabis vapor exposure causes long-term alterations in emotional reactivity, social behavior, and behavioral flexibility in offspring.

Halle V. Weimar, Hayden R. Wright, Collin R. Warrick, Amanda M Brown, Janelle M. Lugo, Timothy G. Freels, Ryan J. McLaughlin

This study shows that prenatal cannabis vapor exposure in rats leads to long-term behavioral changes in offspring, including altered emotional reactivity, social behavior, and cognitive flexibility.

Neuropharmacology · Aug 26, 2020Peer-reviewedNeuroscience

Vaporized cannabis extracts have reinforcing properties and support conditioned drug-seeking behavior in rats

Timothy G. Freels, Lydia N. Baxter-Potter, Janelle M. Lugo, Nicholas C. Glodosky, Hayden R. Wright, Samantha L. Baglot, Gavin N. Petrie, Zhihao Yu, Brian H. Clowers, Carrie Cuttler, Rita A. Fuchs, Matthew N. Hill, Ryan J. McLaughlin

This study shows that vaporized THC-rich cannabis extracts reinforce behavior and increase drug-seeking in rats, supporting their use as a preclinical model for cannabis research.

Journal of Neuroscience · Jan 17, 2020Peer-reviewedNeuroscience

Risky Decision-Making Predicts Dopamine Release Dynamics in Nucleus Accumbens Shell

Timothy G. Freels, Daniel B. K. Gabriel, Deranda B. Lester, Nicholas W. Simon

The paper investigates how dopamine release dynamics in the nucleus accumbens shell correlate with risky decision-making in rats, finding elevated dopamine sensitivity in risk-taking individuals.

Neuropsychopharmacology · Sep 23, 2019Peer-reviewedNeuroscience