Pervasive epistasis modulates neurodevelopmental defects of the autism-associated 16p11.2 deletion
Janani S. Iyer, Mayanglambam Dhruba Singh, Matthew Jensen, Payal T. Patel, Lucilla Pizzo, Emily Huber, Haley Koerselman, Alexis T. Weiner, Paola Lepanto, Komal Vadodaria, Alexis Kubina, Qingyu Wang, Abigail Talbert, Sneha Yennawar, José Luis Badano, , Santhosh Girirajan
The paper identifies genetic interactions within the 16p11.2 deletion that modulate neurodevelopmental phenotypes in Drosophila and links these interactions to human brain networks.
Nature Communications · Jun 25, 2018Peer-reviewedGenomics