Author

Abraham J. Horrillo

Gladstone Institutes

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Genomics· 1

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Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1 Organism:human· 1 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

Frequent Co-Authors

Benoit G. BruneauiD· 1 shared Bing ReniD· 1 shared Bing Yang· 1 shared Carine JoubraniD· 1 shared Irfan S. KathiriyaiD· 1 shared Katherine S. PollardiD· 1 shared Kavitha S. RaoiD· 1 shared Keyi DongiD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Benoit G. BruneauORCID

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1 paper

Recent·Most cited

Dose-dependent sensitivity of human 3D chromatin to a heart disease-linked transcription factor

Zoe L. Grant, Shuzhen Kuang, Shu Zhang, Abraham J. Horrillo, Kavitha S. Rao, Vasumathi Kameswaran, Carine Joubran, Pik Ki Lau, Keyi Dong, Bing Yang, Weronika M. Bartosik, Nathan R. Zemke, Bing Ren, Irfan S. Kathiriya, Katherine S. Pollard, Benoit G. Bruneau

This study shows that reduced TBX5 dosage affects 3D chromatin organization in human cardiomyocytes, with cell-to-cell variation and partial protection by CTCF co-occupancy.

bioRxiv · Jan 9, 2025 · PreprintGenomics