Author

Carine Joubran

Gladstone InstitutesORCID 0000-0002-8747-6954Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:spatial domain detection· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Abraham J. Horrillo· 1 shared Alejandro Aguilera-CastrejoniD· 1 shared Benoit G. BruneauiD· 1 shared Bernardo OldakiD· 1 shared Bing ReniD· 1 shared Bing Yang· 1 shared Cheng ZhaoiD· 1 shared Dmitry Lokshtanov· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Abraham J. Horrillo

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2 papers

Recent·Most cited

Dose-dependent sensitivity of human 3D chromatin to a heart disease-linked transcription factor

Zoe L. Grant, Shuzhen Kuang, Shu Zhang, Abraham J. Horrillo, Kavitha S. Rao, Vasumathi Kameswaran, Carine Joubran, Pik Ki Lau, Keyi Dong, Bing Yang, Weronika M. Bartosik, Nathan R. Zemke, Bing Ren, Irfan S. Kathiriya, Katherine S. Pollard, Benoit G. Bruneau

This study shows that reduced TBX5 dosage affects 3D chromatin organization in human cardiomyocytes, with cell-to-cell variation and partial protection by CTCF co-occupancy.

bioRxiv · Jan 9, 2025 · PreprintGenomics

Transgene-Free Ex Utero Derivation of A Human Post-Implantation Embryo Model Solely from Genetically Unmodified Naive PSCs

Bernardo Oldak, Emilie Wildschutz, Vladyslav Bondarenko, Mehmet-Yunus Comar, Cheng Zhao, Alejandro Aguilera-Castrejon, Shadi Tarazi, Sergey V. Viukov, Thi Xuan Ai Pham, Shahd Ashouokhi, Dmitry Lokshtanov, Francesco Roncato, E. Feldstein Ariel, Max Rose, Nir Livnat, , Jacob H. Hanna

This paper develops a transgene-free human post-implantation embryo model from genetically unmodified naive PSCs, recapitulating key developmental stages and extra-embryonic tissues.

Nature · Sep 6, 2023Peer-reviewedDevelopmental Biology