Insights into the structure and modulation of human TWIK-2
Qianqian Ma, Ciria C. Hernández, Vikas Navratna, Arvind Kumar, Jaimin K. Rana, Jiameng Zong, Abraham Lee, Shyamal Mosalaganti
This study presents the cryo-EM structure of human TWIK-2 and identifies key residues and modulators, providing a foundation for developing anti-inflammatory therapeutics.
Nature Communications · Jan 30, 2026Peer-reviewedBiophysics