Accelerated cognitive decline in obese mouse model of Alzheimer's disease is linked to sialic acid-driven immune deregulation
Stefano Suzzi, Tommaso Croese, Adi Ravid, Or Gold, Abbe R. Clark, Sedi Medina, Daniel Kitsberg, Miriam Adam, Katherine A. Vernon, Eva Kohnert, Inbar Shapira, Sergey Malitsky, Maxim Itkin, Alexander S. Brandis, Tevie Mehlman, , Michal Schwartz
This study shows that obesity accelerates cognitive decline in Alzheimer's mice via sialic acid-driven immune changes.
Nature Communications · Mar 9, 2023Peer-reviewedNeuroscience